February 19 2013, 2:00 pm PT | Posted in: Drugs
I am 27 years old suffering from male pattern baldness for over two years. I want to know whether spironolactone lotion (used on the scalp) really works as some of such brands said:
(1). Spironolactone significantly reduces the amount of DHT in the scalp by inhibiting the conversion of precursor steroids to DHT.
(2). Spironolactone reduces DHT in the scalp by converting localized testosterone into estrogen, which is thought to be protective of the
(3). Spironolactone blocks the follicular androgen receptor sites, thereby rendering any residual or circulating DHT harmless to the hair follicles, and it doesn’t have such side effects as Propecia; and whether it is widely used in treating with male patten baldness.
Thanks for the your answer!
Spironolactone is generally used for treating high blood pressure. While I realize there is a theoretical anti-androgen property associated with spironolactone, there is no conclusive evidence that it really works to re-grow hair. I also realize that many doctors may prescribe spironolactone for hair loss as an “off-label” use, but I personally do not see (or have seen) any benefits from it.
In conclusion, it is still a “buyer beware” mantra that I maintain. It’s also worth noting that Spironolactone has its own list of side effects.